Are YOU at risk of type 2 diabetes? 당뇨병의 '표식', 혈액 중 불포화지방산(unsaturated fatty acids) 함량

Are YOU at risk of type 2 diabetes? Simple blood test could identify those most likely to get disease 10 YEARS before it strikes

확진 10년전에 당뇨병 증세 발견 가능

비만자가 당뇨 일찍 온다는 것은 통념에 불과

미국과 중국, "일반 신체검사" 통해 진단 연구 성과 단계

source thejointblog.com

edited by kcontents 

케이콘텐츠 편집

비만과 II형 당뇨병은 뚜렷한 연관성이 있다는 점은 이미 적지않은 연구에서 밝혀졌다.  그러나 비만자들에게 "향후 당뇨병의 위험수준"에 관한 정보가 일찍 전달된다면 적절한 예방조치를 취할수 있어 위험을 감소한다는 결과가 나타났다. 미국과 중국이 "관례적 신체검사"를 통해 비만자들을 상대로 당뇨병의 위험을 어떻게 확인시켜줄 것인지를 목표로 함께 진행한 연구가 일부 성과를 보이고 있다.     자웨이(賈偉) 미국 하와이대학 암증연구센터 교수가 인솔하는 이 연구에서 혈액중 불포화지방산(unsaturated fatty acids) 함량이 당뇨병 위험을 예시하는 "중요 표식"이고 가장 일찍하게는 확진 10년전에 당뇨병 증세를 발견할수 있다는 내용이 밝혀졌다. 영국 "데일리메일"은 자웨이의 말을 인용해 "사람들은 일반적으로 무릇 비만자에 속하는 이라면 당뇨병 증세가 나타날 가능성이 크다고 생각하지만 사실 '어떤 비만자들은 건강하다'"고 지적하면서 "사람들이 당뇨병 증세를 적절히 간파한다면 보다 핵심적인 조치를 일찍 취할수 있게 된다"고 보도했다. 현재 자웨이가 인솔하는 연구진은 어떻게 하면 혈액채취를 비롯한 간단한 방법으로 당뇨병 위험을 일찍 발견할수 있는지를 향한 연구에 전력을 다하고 있다.[글/ 신화사 기자 어우사(歐颯), 번역/ 신화망 한국어판] [신화사 베이징 11월 4일]

Researchers found fatty acid levels in blood are markers of pre-diabetes - a condition that usually develops into full-blown type 2 diabetes

Fatty acid levels change in the blood up to 10 years before diabetes strikes

Blood test to identify those at risk could be given during routine check ups

Test could give advanced warning so people can change their lifestyles 

By MADLEN DAVIES FOR MAILONLINE

A simple blood test could identify who is at risk of developing diabetes, a study has found.

The test could give individuals years of advanced warning so they can change their lifestyles and potentially avoid diagnosis, researchers said.

It could also identify people who are overweight but are not in any danger of developing the disease.

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A simple blood test could identify who is at risk of developing diabetes 10 years before the disease strikes, allowing individuals to change their lifestyles and potentially avoid diagnosis

Scientists discovered that levels of unsaturated fatty acids in the blood are markers of pre-diabetes, high blood sugar levels that can predict the onset of type 2 diabetes.

These fatty acid levels can change up to 10 years before full-blown diabetes develops, they found.

The researchers are now developing a blood test to identify those at risk which could be carried out during routine physical check ups in future.

Lead researcher Dr Wei Jia, of the University of Hawai'i Cancer Center, said: 'Currently there are no clinical tests that tell you the likelihood of developing diabetes, only exams that tell you, for example, if someone that is pre-diabetic has relatively high blood sugar or insulin levels.

'To know if you are likely to get diabetes in a few years is an important discovery. 

'People can hopefully get tested for the disease during physical exams in the future.'

NEW SMARTPHONE DEVICE TO DETECT DIABETES IN SECONDS 

Diabetes can be detected in a saliva sample using a revolutionary new smart phone device.

Researchers say the device - which should be available within two years - will provide immediate results and could be used to diagnose the problem in low-income areas.

It was developed by scientists at Tec de Monterrey in Mexico with colleagues at the University of Houston in the US.

They say what makes the new development unique is that it is adaptable to mobile phones and gives results in a few seconds, avoiding the use of needles.

It is a cartridge adaptable to a mobile that records if a compound is present in saliva, which becomes visible if the patient has diabetes.

Project coordinator Doctor Marco Antonio Rite Palomares, director of the Biotechnology Center at Tec de Monterrey, said: 'It's as simple as pregnancy tests, where the specific marker shows in a few seconds.'

He said the project is planned to be completed within two years, adding: 'We wanted a device which could identify a biomarker in a sample of saliva, and it had to emit fluorescent light so a phone camera could record it.'

Conventionally, it is assumed that people who are obese are at risk of being pre-diabetic, he continued.

'However, sometimes people who are obese can still be healthy,' he said.

'If people know they are specifically pre-diabetic, they can have a more targeted way of treating it.'

Obesity is associated with type 2 diabetes, non-alcoholic fatty liver disease, heart problems and cancer.

However, around 25 to 40 per cent of obese individuals can be fat but metabolically healthy, showing no apparent signs of health complications, researchers said.

Dr Wei and his team, who worked in collaboration with scientists at Shanghai Jiao Tong University affiliated Shanghai 6th People's Hospital, studied 452 people split into four groups.

They looked at metabolically healthy and unhealthy obese subjects, observing the occurrence of pre-diabetes over ten years.

They discovered levels of unsaturated fatty acids in the blood are markers of pre-diabetes.

The levels of these fatty acids can change up to 10 years before the individuals are diagnosed with the disease.

Taking a blood sample could predict the risk of developing pre-diabetes and diabetes and metabolic syndrome, which is a group of conditions including elevated blood pressure, insulin resistance and high blood sugar level.

This could allow physicians to warn people years before the onset of diabetes, allowing them to change their lifestyle patterns and potentially avoid ever developing the disease.

The researchers are developing the technology to test blood, and aim to make it available to health professionals.

The study was published in the journal EBioMedicine. 

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The test could also identify people who are overweight but are not in any danger of developing the disease

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